KOREASCHOLAR

콩깍지 추출물의 항산화·항염·항비만 및 에스트로겐 유사활성 평가 Antioxidant, Anti-inflammatory, Anti-obesity and Estrogen-like Activities of Soybean Pod Extracts

정은숙, 김행란, 황유진, 장경아, 서미경, 추한나
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  • URLhttps://db.koreascholar.com/Article/Detail/412093
韓國食生活文化學會誌 (한국식생활문화학회지)
제36권 제6호 (2021.12)
pp.649-660
한국식생활문화학회 (The Korean Society Of Food Culture)
초록

In this study, soybean pods of 45 soybean landraces (or varieties) were classified as yellow (19 samples), black (23 samples), or black in green (3 samples) based on soybean seed coat color. Total polyphenol and flavonoid contents were measured, and antioxidant, anti-inflammatory, anti-obesity, and estrogen-like activities were assessed. Total polyphenol and flavonoid content ranges were 24.13-108.03 mg GAE/g and 3.31-72.02 mg CE/g, respectively, and were highest in the black group followed by the yellow group and were least in the black in green group, while ABTS and DPPH activities followed the order black in green > black > yellow. Estrogen-like and estrogen receptor-α activity ranges were 29.06-35.58 pg/mL and 7.05-10.13 pg/mL and were followed the order yellow > black > black in green and black in green > yellow > black, respectively. Nitric oxide (NO) inhibitory and UCP-1 activities followed the same order as estrogen receptor-α activities. Our findings suggest that soybean pods are excellent sources of antioxidants and high-quality functional materials.

키워드
Functional componentsphysiological activitysoybean podsestrogen-like activityantioxidant activity
목차
Abstract
I. 서 론
II. 연구 내용 및 방법
    1. 실험 재료
    2. 총 폴리페놀 및 총 플라보노이드 함량
    3. 항산화 활성 평가
    4. 세포 배양
    5. Estrogen과 estrogen receptor-α (ER) 유사 활성
    6. Nitric oxide (NO) 억제 활성
    7. UCP-1 (갈색지방 전환능) 활성
    8. 통계 처리
III. 결과 및 고찰
    1. 콩깍지의 총 폴리페놀 및 총 플라보노이드 함량
    2. 콩깍지의 항산화 활성
    3. Estrogen과 estrogen receptor-α (ER) 유사활성
    4. Nitric oxide (NO) 억제 활성 측정
    5. C3H/10T/1/2 세포에서 항비만 활성(UCP-1 발현) 측정
IV. 요약 및 결론
References
저자
  • 정은숙(국립농업과학원 농식품자원부) | Eun-Suk Jung (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA)
  • 김행란(국립농업과학원 농식품자원부) | Haeng-Ran Kim (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA)
  • 황유진(국립농업과학원 농식품자원부) | Yu-Jin Hwang (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA)
  • 장경아(국립농업과학원 농식품자원부) | Kyeong-A Jang (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA)
  • 서미경(국립농업과학원 농식품자원부) | Mi-Kyung Seo (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA)
  • 추한나(국립농업과학원 농식품자원부) | Han-na Chu (Department of Agrofood Resources, National Institute of Agricultural Sciences, RDA) Corresponding author