Spraque-Dawley계 웅성흰쥐에 계통분획한 소엽의 각 분획물을 경구투여하고 혈청 Ethanol농도와 간의 ADH활성에 미치는 효과를 검색 추적한 결과 알코올대사를 촉진시키는 성분은 주로 에탄올가용부에, 억제시키는 성분은 에탄올불용부에 주로 존재함을 추정할 수 있었고 현재 활성성분을 분리중에 있다.

Effects of organic solvent fractions from perilla ethanol extract on alcohol metabolism in rats were examined and the results were as follows: Ethanol souble fraction, after a single oral administration to rats, was found to cause a significant decrease in the serum ethanol concentration as well as enhancement of liver cytosolic alcohol dehydrogenase (ADH) activity. On the other hand, the fraction insouble in ethanol was found to increase ethanol concentration in the blood and inhibit ADH activity.

• 문형인 | Moon, Hyung-In
• 지옥표 | Zee, Ok-Pyo
• 신국현 | Shin, Kuk-Hyun