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추출 공정 다변화를 통한 홍경천의 항암활성 증진효과 KCI 등재

Increase Effect of Anticancer Activities on Rhodiola sachalinensis A. Bor by the Change of Extraction Process

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한국약용작물학회지 (Korean Journal of Medical Crop Science)
한국약용작물학회 (The Korean Society of Medicinal Crop Science)
초록

This study was performed to compare effect of anticancer activities on Rhodiola sachalinensis by ultrasonifi-cation process and solvent. Compared the yield to the water extracts (WE), wafer extracts with ultrasonification (WEU) at60, loot and ethyl alcohol extracts (EE), ethyl alcohol extracts with ultrasonification (EEU) at 60 ˚C from Rhodiola sachalinensis. Experimental studies were progressed through the anticancer activities such as cell cytotoxicity, inhibition activities of cell growth. The cell cytotoxicity using human embryonic kidney cell (HEK293) was showed cytotoxicity of below 26.26%by extracts of Rhodiola sachalinensis in 1.0 mg/ml concentration, The anticancer activities were increased in over 70% by extracts of Rhodiola sachalinensis in A549, AGS, Hep3B and MCF-7 cells. From the results, the extract Rhodiola sachalinensis were showed useful anticancer activities.

저자
  • 김철희 | Kim, Cheol-Hee
  • 김효성 | Kim, Hyo-Sung
  • 권민철 | Kwon, Min-Chul
  • 배근중 | Bae, Geun-Jung
  • 안주희 | Ahn, Jup-Hee
  • 이학주 | Lee, Hak-Ju
  • 강하영 | Kang, Ha-Young
  • 이현용 | Lee, Hyeon-Yong