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새로운 Aminopyrimidinylmethanone 유도체의 합성 KCI 등재

Synthesis of New Aminopyrimidinylmethanone Derivatives

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  • URLhttps://db.koreascholar.com/Article/Detail/257705
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한국응용과학기술학회지 (The Korean Society of Applied Science and Technology)
한국응용과학기술학회(구 한국유화학회) (The Korean Society of Applied Science and Technology (KSAST))
초록

In this work, the synthetic approaches for a series of aminopyrimiclinylmethanone derivatives 1a-i, which versatile biological activities such as antibacterial and anticancer activities are expected from a structural point of view, were described. Nicotinic acid was converted to (2-methylsulfonylpyrimidin-4-yl) (pyridin-3-yl)methanone, a key intermediate, which was reacted with nucleophiles to yield the desired aminopyrimidinylmethanone derivatives 1a-i bearing various substituents.

저자
  • 유경호 | Yoo, Kyung-Ho
  • 안혜미 | Ahn, Hye-Mi