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Screening for Anti-diabetic Effects of Prescribed Korean Traditional Medicines

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  • URLhttps://db.koreascholar.com/Article/Detail/259181
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한국자원식물학회지 (Korean journal of plant resources)
한국자원식물학회 (The Plant Resources Society Of Korea)
초록

Herb extracts commercially used in Korea were screened for PPAR-γ agonist test and α-glucosidase inhibition assay. Total 16 herb plants had a PPAR-γ agonist activity. Specially, Alisma orientale Juz (108.41%), Ephedra sinica (98.22%), Sasa japonica Makino var. purpurascens Nakai (140.68%), Astragalus membranaceus Bunge (106.79%) and Cnidium officinale Makino (113.00%) showed high PPAR-γ agonist activity rate compared with rosiglitazone's (167.46%). And Cornus officinalis S. et Z. (90.3%), Cinnamomum cassia Blume (89.2%), Psoralea corylifolia L. (89.8%), Paeonia japonica (Makino) Miyabe (92.4%) and Paeonia suffruticosa Andr (93.2%), showed high α-glucosidase inhibition rates. These results support previous reports of the efficacy of Oriental medicinal plants used for diabetes mellitus.

저자
  • Seon Mi Shin
  • Yong Joon Jeong
  • Dae Won Park
  • Heung Ko
  • Gi Tae Kim
  • Ee-Hwa Kim
  • Taeseong Kim
  • Eun-Hwa Sohn
  • Jung-Eun Kwon
  • Hyun Jung Koo
  • Se Chan Kang