An experimental study was performed to investigate the cyclic behavior of steel plate walls with reinforced concrete frames. Three specimens of three-story steel plate walls with reinforced concrete frames were tested. The parameters for the test specimens were the reinforcement ratio of the column and coupling wall. A reinforced concrete infilled wall and a reinforced concrete frame were also tested for comparison. The steel plate walls with reinforced concrete frames exhibited much better ductility and energy dissipation capacity than the reinforced concrete infilled wall and the reinforced concrete frame. The results showed that unlike other structural systems, the steel plate wall with reinforced concrete frames has excellent deformation capacity as well as strength, and can therefore be used as an effective earthquake-resisting system. This result indicates that not only steel frames but also reinforced concrete frames can be used in the steel plate wall system.