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더덕 잎, 줄기, 뿌리 부위의 Triterpenoid 사포닌 함량 KCI 등재

Triterpenoid Saponin Contents of the Leaf, Stem and Root of Codonopsis lanceolata

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한국약용작물학회지 (Korean Journal of Medical Crop Science)
한국약용작물학회 (The Korean Society of Medicinal Crop Science)
초록

Codonopsis lanceolata (Campanulaceae) has been used in traditional medicines, as its roots contain severalkinds of 3,28-bidesmosidic triterpenoid saponin with high medicinal values. In this study, we induced hairy root-derivedtransgenic plants of C. lanceolata and analyzed triterpenoid saponins from the leaf, stem and root. Transgenic plants wereregenerated from the hairy roots via somatic embryogenesis. The saponins are lancemaside A, B and E, foetidissimoside A,and aster saponin Hb. Transgenic plants contained richer triterpenoids saponin than wild-type plants. Major saponin lance-maside A was the most abundant saponin in the stem from transgenic-plant, 4.76㎎·1−¹ dry stem. These results suggest thattransgenic plants of C. lanceolata could be used as medicinal materials for the production of triterpene saponins.

저자
  • 김지아(국립산림과학원 산림생명공학과) | Ji Ah Kim Corresponding author
  • 문흥규(국립산림과학원 산림생명공학과) | Heung Kyu Moon
  • 최용의(강원대학교 산림자원학과) | Yong Eui Choi