This study was conducted to investigate the physiological activities of the ethanol extracts from 3 different strains of Hericium erinaceum. In addition, the β-glucan and polyphenol contents from these strains were also measured. As a result, total polyphenol contents were the highest in 1ho(39.07 mg%) strain and lowest in 2ho(17.59 mg%). β-glucan contents ranged from 17.69 to 18.26%. In the physiological activities, Inhibition effects of DPPH radical and Nitrite ranged from 3.29 to 9.6% and 1.52 to 5.27%, respectively. Inhibitory effects of nitric oxide production ranged from 23.72 to 33.47%. The highest inhibitory activities on α-amyloglucosidase activity and angiotensin I converting enzyme were 39.30% and 14.10%, respectively. Lastly, the cytotoxic activities of ethanol extracts from all the strains on A549, HT-29 and HeLa cell was shown the highest effect in A549 cell.

• Se-hyun Jo(Department of Food Science & Biotechnology, Sungkyunkwan University)
• Taeho Kim( Department of Food Science & Biotechnology, Sungkyunkwan University) | Taeho Kim
• Young-bok Yu( Mushroom research Division, National Institute of Horticultural & Herbal Science, RDA, Suwon 441-707, Korea) | Young-bok Yu
• Ki-Moon Park( Department of Food Science & Biotechnology, Sungkyunkwan University,) | Ki-Moon Park