Changes in the business environment in which intense and sustained growth and survival must meet a variety of customer needs (Q, C, D) and business side of the enterprise for profit structure reformation is absolutely necessary for innovation activities. So far, management of innovation in method BPR, PI, OVA, 6 Sigma, Strategic Purchasing, PPM, SCM etc. are being introduced. However, they have a limit of partial optimization and improvement-oriented techniques. So this paper studied the TPI(Total Profit Innovation) application in order to derive empirical methodology to maximize profitability for the domestic S foundry factory. To this end, long-term gains through structural analysis and intensity analysis to ensure continued growth and profitability strategy are devised through management Innovation analysis. And improvement projects was presented to solve main issues of five categories(Inventory, Sales Mix, Cost, Quality Cost, Skill and Work-load) We will expect the office productivity improvement and financial performance improvement and then continually accumulate and review the results.