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류마티스 관절염 환자에서 Bucillamine에 의한 신병증 1례

Bucillamine-induced Nephropathy in a Patient with Rheumatoid Arhtritis

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The Medical Journal of Chosun University (조선대학교 의대논문집)
조선대학교 의학연구원 (Institute of Medical Science, Chosun University)
초록

There are many known renal complications of rheumatoid arthritis. These complications can develop by the extraarticular aspect of rheumatoid arthritis or the use of disease modifying antirheumatic drugs or pain-killer. The most common renal disease induced by use of disease modifying antirheumatic drugs is membranous nephropathy. We report on a case of bucillamine induced nephropathy with prominent proteinuria and hypoalbuminemia. The renal biopsy result was stage I to II membranous nephropathy. After withdrawal of bucillamine the proteinuria improved and hypoalbuminemia recovered. Even in cases of accompanying prominent proteinuria and hypoalbuminemia, bucillamine nephropathy can be treated with withdrawal of bucillamine and immunosuppressant drugs are not required.

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저자
  • 남경민(Departments of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea) | Kyung Min Nam
  • 박장호(Departments of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea) | Jang Ho Park
  • 변상환(Departments of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea) | Sang Hwan Byun
  • 조영선(Departments of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea) | Young Sun Jo
  • 김현주(Departments of Internal Medicine, Wallace Memorial Baptist Hospital, Busan, Korea) | Hyun Ju Kim Corresponding author