In this study, we examined the spatial dependence and association of Ambrosia beetle, Platypus koryoensis, which is the vector of oak wilt disease caused by Rafaelea sp. using two geostatistical methods. Two adjacent sampling plots were selected and named as "Sector A" and "Sector B". Sector A area was 63 ha and Sector B area was 420 ha, respectively. We arbitrarily separated each sampling plot by 50m×50m grids. Sector A and B were separated by 19×15 and 43×41 grids, respectively. The oak wilt disease damage level of tree was classified by amount of frass of Ambrosia beetle near target oak tree as follows: Lost tree (LT), Severe damage (SD), Intermediate damage (ID), and Light damage (LD). Number of each damage level of oak tree was counted and recorded in each sampling grid. Spatial dependence and association of oak wilt damage was analyzed and compared using mathematical variogram models and spatial analysis by distance indices (SADIE). Variogram model ranges were 179~368m in Sector A and 634~1073m in Sector B, respectively. The damage levels of all trees in each sector were indicated as aggregated distribution by aggregation indices of SADIE (Ia > 1). Each damage level pair had strong association in the consecutive orders than in any random order based on the results of SADIE association test. The spatial dependence and association of oak wilt damage levels presented here provide the baseline information necessary to understand and manage oak wilt disease in Korea.