Odontogenic keratocysts(OKCs) are frequently associated with erupted or impacted tooth. In such instances, the radiographic features simulate those of a dentigerous cyst. The purpose of this study was to evaluate a comparative immunohistochemical expression of Ki-67 as a proliferative marker and apoptotic signals in the OKC associated with or without impacted tooth. In addition, we have also been investigated with regard to the proliferative activity and apoptosis comparing the unilocular and multilocular varieties of the OKC. The material for this study consisted of thirty-two cases of OKCs (OKC with impacted tooth, n=16；OKC without impacted tooth, n=16) and ten cases of dentigerous cysts as a comparison. The results revealed that the proliferative activity and apoptosis of OKCs with impacted tooth was higher than those of dentigerous cysts. However, there was no correlation between Ki-67 immunoreactivity or apoptosis and association with or without impacted tooth in 32 cases of OKCs. In addition, this present study showed that there was no correlation between the unilocular and multilocular varieties of the OKCs in proliferative activity and apoptosis.

I. 서 론
 II. 연구 대상 및 방법
  가. 연구 대상
  나. 연구 방법
 III. 연구 결과
 IV. 고 찰
 V. 결 론
 참고 문헌

• 윤정훈(조선대학교 치과대학 구강병리학교실) | Jung Hoon Yoon
• 김도경(구강생리학교실) | Do Kyung Kim Corresponding Author