Algae-related taste and odor problems are recognized by the water community worldwide to be major causes of consumer complaints and a loss in confidence of drinking water safety by the general public. Such problems can be arisen by natural and anthropogenic means, even by drinking water treatment processes. Microorganism is a common cause of naturally produced taste and odor. In this connection, the role of microorganisms and their metabolites are reviewed in the viewpoint of taste and odor in drinking water supplies.