Low level light therapy (LLLT) is known to accelerate the process of wound healing, bone and cartilage formation, and to decrease tissue necrosis and inflammation. It also can be applicable to acute and chronic injury or degenerative disease. Despite forty- plus years of accumulating exprerience of the clinical efficacy of LLLT, their molecular biologic evidence is not fully elucidated. The aim of this review is to explore the role of the ROS system and its molecular biologic mechanism in related with inflammatory response, anti-apoptosis and angiogenesis during LLLT. We suggest that activation of ROS system explains many (if not most) of the observed response of cells to LLLT in vitro, and is likely to play a pivotal role in the response of animals and patients to LLLT for both experimental and clinical indications and diseases.

Ⅰ. 서론
  1. 저출력 광 조사에 따른 세포 내 ROS의 조절
  2. 저출력 광조사에 따른 염증성 반응의 조절
  3. 저출력 광조사에 따른 세포 자멸사의 억제
  4. 저출력 광조사에 따른 혈관 신생
 Ⅲ. 결론
 Ⅳ. References

• 임원봉(전남대학교 치의학전문대학원 구강병리학교실 및 치의학연구소) | Won Bong Lim
• 최홍란(전남대학교 치의학전문대학원 구강병리학교실 및 치의학연구소) | Hong Ran Choi
• 김병국(전남대학교 치의학전문대학원 구강내과 및 치의학연구소) | Byung Kuk Kim
• 김지선(전남대학교 치의학전문대학원 구강병리학교실 및 치의학연구소) | Ji Sun Kim
• 김옥준(전남대학교 치의학전문대학원 구강병리학교실 및 치의학연구소) | Ok Joon Kim correspondence