Odontogenic cyst and odontogenic tumor shares developmental source. However, they have different histopathologic features, and they are classified respectively. Odontogenic cyst and tumor can share same physical region. It is called a hybrid lesion, a lesion showing the combined histopathological characteristics of two or more previously recognized odontogenic tumor and/or cysts of different categories. In this study, a hybrid lesion was researched. 61-year old man was referred to our department with a multilocular radiolucency in right mandibular angle. Incisional biopsy was carried out, and the patient was diagnosed with ameloblastoma. Odontogenic keratocyst was found with the tumor, and it was thought to be evolved via neoplastic transformation from lining epithelium of the keratocyst. After reviewing studies reporting hybrid lesions from odontogenic cyst and tumor, formation of a hybrid lesion was most frequent from a dentigerous cyst and an adenomatoid odontogenic tumor. A hybrid lesion commonly lead to misdiagnosis, and the prognosis is not always transparent. The close relationship between the odontogenic cyst and tumor has to be kept in mind in the diagnosis and treatment of the lesions in maxillofacial area.

• 권오인(전남대학교 치의학전문대학원 구강병리학교실) | Oh in Kwon
• 전상미(전남대학교 치의학전문대학원 구강병리학교실) | Sang Mi Jeon
• 김지선(전남대학교 치의학전문대학원 구강병리학교실) | Ji Sun Kim
• 김상우(전남대학교 치의학전문대학원 구강병리학교실) | Sang Woo Kim
• 최홍란(전남대학교 치의학전문대학원 구강병리학교실) | Hong Ran Choi
• 김옥준(전남대학교 치의학전문대학원 구강병리학교실) | Ok Joon Kim Corresponding author