Syphilis is a sexually transmitted infection caused by Treponema pallidum. Ocular involvement is rare and diagnosis of ocular
syphilis is challenging due to nonspecific symptoms. The diverse manifestation of ocular syphilis occurs as well in secondary
as in tertiary syphilis, for it can affect all structures of the eye; corneoscleral, uveal, retinal, and optic nerve inflammation
may be observed. We report on a case of ocular syphilis affecting the vitreous body in a 43-year-old healthy male
with a 6-month history of diminished visual acuity in the left eye.