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RNA Interference of β-Integrin Expression Reduces Survival of Phaedon brassicae (Coleoptera: Chrysomelidae)

  • 언어ENG
  • URLhttps://db.koreascholar.com/Article/Detail/313034
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한국응용곤충학회 (Korean Society Of Applied Entomology)
초록

Integrin is a heterodimer protein that locates on cell membrane to interact with neighboring cells or extracellular matrix. A transcriptome analysis of the brassica leaf beetle, Phaedon brassicae, midgut identified both α and β subunits of integrin. RNA interference of β subunit genes significantly impaired survival of both larvae and adults of P. brassicae. A recombinant bacteria expressing double-stranded RNA specific to β integrin of P. brassicae were constructed and showed significant oral toxicities.

저자
  • Eunseong Kim(Department of Bioresource Sciences, College of Natural Sciences, Andong National University)
  • Md Sadekuzzaman(Department of Bioresource Sciences, College of Natural Sciences, Andong National University)
  • Youngjin Park(Department of Bioresource Sciences, College of Natural Sciences, Andong National University)
  • Yonggyun Kim(Department of Bioresource Sciences, College of Natural Sciences, Andong National University)