Biological control has been tried for integrated pest management. It is often comparable, safe, and environment-friendly, making itself an alternative for chemical agents. Filamentous microorganisms, i.e., fungi and streptomystes, produce many kinds of useful metabolites, and some of them have been developed as a biocontrol agent. However, they still have a long way because of the concern of manufacturing cost. Therefore, process development was intensively studied to meet cost-effectiveness. Operating conditions of bioreactor, e.g., agitation and aeration, had an effect on biological and physiological responses such as mycelial morphology, oxygen and nutrient transfer. Understanding relationship between operating parameters and microbial responses in terms of growth, substrate and oxygen consumption, and production yield was critical for process development. This study dedicated to build strategies for mass production of biological control agent using aerobic filamentous microorganisms.

• Hae Woong Park(R&D division, World Institute of Kimchi)
• Sang Il Lee(R&D division, World Institute of Kimchi)
• Keon Jin Lee(R&D division, World Institute of Kimchi)
• Sanghyun Ha(R&D division, World Institute of Kimchi)
• Hyun Jung Gwak(R&D division, World Institute of Kimchi)
• Ae Ri Han(R&D division, World Institute of Kimchi)
• Young Bae Chung(R&D division, World Institute of Kimchi)
• Ho Hyun Chun(R&D division, World Institute of Kimchi)
• Hyeyeon Song(R&D division, World Institute of Kimchi)