논문 상세보기
pp.417-425
목적: 본 연구는 trimethylsilyl methacrylate와 titanium silicon oxide 나노입자를 사용하여 친수성 하이드로젤 콘택트렌즈 재질을 중합하고 제조된 친수성 콘택트렌즈의 물리적, 광학적 특성을 분석하여 이들 물질들의 콘택트렌즈 재료로서의 활용도를 알아보았다. 방법: 고분자의 중합은 2-hydroxyethyl methacrylate, methyl methacrylate 및 n-vinyl pyrrolidone과 가교제인 ethylene glycol dimethacrylate를 기본 조합으로 하였으며, 개시제로는 AIBN을 사용하였다. 제조된 렌즈의 물성 변화를 알아보기 위해 trimethylsilyl methacrylate와 titanium silicon oxide를 첨가하여 중합하고 함수율, 굴절률, 산소투과도, 분광투과율을 측정하였다. 결과: 제조된 친수성 콘택트렌즈는 하이드로젤 콘택트렌즈의 기본물성을 만족하였으며, 첨가제인 trimethylsilyl methacrylate의 양이 증가함에 따라 산소투과도는 증가하는 것으로 나타났다. 또한 titanium silicon oxide 나노입자의 첨가는 친수성 렌즈 소재의 기본적인 물성을 변화시키지 않으면서 자외선을 차단하는 것으로 나타났다. 결론: 본 연구를 통해 trimethylsilyl methacrylate와 titanium silicon oxide는 콘택트렌즈의 기본적인 물성을 만족시키면서 고산소투과성 및 자외선 차단 콘택트렌즈 재료로 다양하게 활용될 수 있을 것으로 판단된다.
Purpose: This study evaluated the physical and optical characteristics of hydrophilic contact lens polymerized with addition of trimethylsilyl methacrylate and titanium silicon oxide in the basic hydrogel contact lens material, and in particular, this study investigated the utility of TMSMA and TiSiO4 nanoparticles as a contact lens material for ophthalmologic devices. Methods: In this study TMSMA and TiSiO4 nanoparticles were used as additives. 2-hydroxyethyl methacrylate, methyl methacrylate, n-vinyl pyrrolidone and a cross-linker EGDMA were copolymerized in the presence of AIBN as an initiator. We measured physical properties such as water content, refractive index, oxygen permeability, spectral transmittance of produced contact lenses. Results: The hydrogel contact lens material produced using trimethylsilyl methacrylate satisfied the basic characteristics required for contact lenses and also showed an increase in oxygen permeability. The physical properties measurements of the produced contact lenses showed that the added titanium silicon oxide nanoparticles did not show significant effect on the basic physical properties, but the materials have UV-blocking property. Conclusions: Based on the results of this study, contact lens material containing TMSMA and TiSiO4 is expected to be able to be used usefully as a material for high oxygen permeability and UV-block hydrogel contact lens.
