In this study, we determined the effect of the mulberry leaf powder on blood lipid metabolism and liver function improvement of mice fed a high fat diet. The mulberry leaf showed a moisture content of 10.74±0.56%, ash 9.67±0.56%, crude protein 25.24±1.02%, and crude fat 2.66±0.08%. In the group with high fat diet supplemented with mulberry leaf powder, serum low-density lipoprotein (LDL-cholesterol) and total cholesterol levels were significantly lower (p<0.05); also, serum phospholipid and aspartate amino transferase (AST) levels were significantly lower (p<0.05). Serum insulin and leptin levels were high in mice fed a high fat diet; however, addition of mulberry leaf powder 10% in the diet had no significant effect on blood insulin and leptin control. The results of the study suggested that various plant sterols in mulberry leaf improve lipid metabolism and liver function in ICR-mice.

서 론
 재료 및 방법
  1. 일반성분 분석
  2. 실험동물 및 사육조건
  3. 동물사료 조성
  4. 평균체중 변화율 및 사료섭취량
  5. 혈액 채취
  6. 혈중 지질 농도 분석
  7. 혈액 내 생화학적 분석
  8. 통계처리
 결과 및 고찰
  1. 일반성분 분석
  2. 평균체중 변화율 및 사료섭취량
  3. 혈중 지질 농도
  4. 혈중 인지질과 간 기능
  5. 혈중 인슐린과 렙틴 농도
 요약 및 결론
 References

• 최경순(삼육대학교 식품영양학과) | Kyung-Soon Choi
• 김용환(경기대학교 식품생물공학과) | Yong-Hwan Kim
• 신경옥(삼육대학교 식품영양학과) | Kyung-Ok Shin Corresponding author