The widely accepted recognition of global environmental problems has resulted in a paradigm shift for research in the hydrosciences. Hydrologic model has played important roles in hydroscience and engineering. However, there are some limitations to deal with real world problems. In this paper, comprehensive review on the current status and major issues on hydrologic models. The sources of model uncertainty were classified and discussed. Finally, model calibration and verification issues were discussed in view of Popperian perspective.