In this paper, seismic performance assessment has been examined for a mid-rise RC building subjected to 2016 Gyeongju earthquake occurred in Korea. For the purpose of the paper, 2D external and internal frames in each direction of the building have been employed in the present comparative analyses. Nonlinear static pushover analyses have been conducted to estimate frame capacities. Nonlinear dynamic time-history analyses have also been carried out to examine demands for the frames subjected to ground motions recorded at stations in near of Gyeongju and a previous earthquake ground motion. Analytical predictions demonstrate that maximum demands are significantly affected by characteristics of both spectral acceleration response and spectrum intensity over a wide range of periods. Further damage potential of the frames has been evaluated in terms of fragility analyses using the same ground motions. Fragility results reveal that the ground motion characteristics of the Gyeongju earthquake have little influence on the seismic demand and fragility of frames.