The hollow slab has advantages that its self-weight does not greatly increase notwithstanding the increase of its thickness and its flexural performance does not significantly degrade in comparison with general reinforced concrete slab. However, the utilization of the hollow slab is currently being underestimated in spite of structural system that enables economic design of building and construction of eco-friendly structure. the significant reasons for this situation is that the method of structural analysis and design for hollow slab is not generalized. In this study, to consider practical compressive zone of hollow slab, the equation for its flexural strength is proposed by the volume of compressive stress block according to neutral axis location in hollow section assumed. Existing estimation method of flexural strength of hollow slab considering only compressive zone above hollow part is evaluated as the most conservative method and the method estimating flexural strength by two alternative cross-section of hollow slab is evaluated as more practical method.