The objective of this research is to examine how the lateral resisting system of selected prototypes are affected by seismic zone effect and shape irregularity on its seismic performance. The lateral resisting systems are divided into the three types, diagrid, braced tube, and outrigger system. The prototype models were assumed to be located in LA, a high-seismicity region, and in Boston, a low-seismicity region. The shape irregularity was classified with rotated angle of plane, 0°, 1°, 2°. This study performed two parts of analyses, Linear Response and Non-Linear Response History(NLRH) analysis. The Linear Response analysis was used to check the displacement at the top and natural period of models. NLRH analysis was conducted to invest base shear and story drift ratio of buildings. As results, the displacement of roof and natural period of three structural systems increase as the building stiffness reduces due to the changes in rotation angle of the plane. Also, the base shear is diminished by the same reason. The result of NLRH, the story drift ratio, that was subject to Maximum Considered Earthquake(MCE) satisfied 0.045, a recommended limit according to Tall Building Initiative(TBI).