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백서 두개골에서 LED 조사가 골 형성에 미치는 영향 KCI 등재

Effects of LED irradiation on bone formation in rat calvaria

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  • URLhttps://db.koreascholar.com/Article/Detail/324740
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대한구강악안면병리학회지 (The Korean Journal of Oral and Maxillofacial Pathology)
대한구강악안면병리학회 (Korean Academy Of Oral And Maxillofacial Pathology)
초록

μ방lt emitting diodes (LED) devices are commercially introduced as an alternative for low-Ievellaser therapy (11ι,T) , and it has several advantages over lasers such as a safe, efficient, and less-expensive altemative to treat wounds. And LED irradiation at the same biostimulatory wavelength has similar bíochemical effεαs. In the present study, to asses whether the I핑ht-emitting diode (LED) irradíation can stimulate bone regeneration, irradiated bony defects with or without grafting materials on rat calvaria were compared to corresponding nonirradiated control. Fifty male Sprague-Dawly rats weighing about 150g, were used. Factors for present study were designed as follows, 1) presence or absence of grafting materials, 2) with or without irradiation, and 3) number of irradiation. Two weeks after operation, rats were sacrifìced. Radiologic and 비stomorphologic fmdings were evaluated. Macrospically, there were no incidents of infection, dehiscence, hematoma and necrosis during study. Radiological findings showed greater radiopacity in the graft group and radiopacity increased as the number of irradiation increase. And microscopically, new bαle formation was great in the graft group and increased as the number of irradiation increase, Present study has shown that LED irradiation improved bone regeneration through radiologic and histomorphologic fmdings in rat.

저자
  • Sae WOO Han(Departrnent of Oral Pathology, Dental Science Research Institute) | 한세우
  • Ok Joon Kim(Departrnent of Oral Pathology, Dental Science Research Institute) | 김옥준
  • Youn young Jang(Departrnent of Oral Pathology, Dental Science Research Institute) | 장윤영
  • Won Bong Lim(Departrnent of Oral Pathology, Dental Science Research Institute) | 임원봉
  • Oh Won Mann(Departrnent of Oral Pathology, Dental Science Research Institute) | 오원만
  • Jin Soo Park(Biophoton) | 박진수
  • Myung Rae Kim(Department of OromaxilJosurgery, Mokdong Hospital, Ewha Womans University) | 김명래
  • Hong Ran Choi(Departrnent of Oral Pathology, Dental Science Research Institute) | 최홍란