Embryo development is very important in reproductive physiology of domestic animal experiments. Therefore, in the above experiment, we want to provide a lot of important information with regard to fertilization breeding by looking at the expression of transcription factor by early embryo development. It is known that mice affect early embryonic development of many transcription factors, many experiments are underway. Different types of mammals showed different expression patterns, thus, we used pigs, which are known to be the most similar to humans, to observe the expression of transcription factors in early embryonic development. Transcription factors were observed using CDX2, OCT4 and E-CADHERIN. CDX2 was expressed in 2 cells, OCT4 and E-CADHERIN were expressed in blastocyst. OCT4 was expressed specifically in ICM (inner cell mass) in blastocyst, and E-CADHERIN was expressed in cell wall and junction of blastocyst. These results show that CDX2, OCT4 and E-CADHERIN play an important role in early embryonic development in pigs.

• So Yeon Kim(Department of Animal Science & Biotechnology, Research Center for Transgenic Cloned Pigs, Chungnam National University)
• Tao Lin(Department of Animal Science & Biotechnology, Research Center for Transgenic Cloned Pigs, Chungnam National University)
• Reza K. Oqani(Department of Animal Science & Biotechnology, Research Center for Transgenic Cloned Pigs, Chungnam National University)
• Jae Eun Lee(Department of Animal Science & Biotechnology, Research Center for Transgenic Cloned Pigs, Chungnam National University)
• Jung Won Kang(Department of Animal Science & Biotechnology, Research Center for Transgenic Cloned Pigs, Chungnam National University)
• Joo Bin Lee(Department of Animal Science & Biotechnology, Research Center for Transgenic Cloned Pigs, Chungnam National University)
• Dong Il Jin(Department of Animal Science & Biotechnology, Research Center for Transgenic Cloned Pigs, Chungnam National University)