Social needs are increasing due to the increase of degenerative brain diseases because of the aging society. The most common type of degenerative brain diseases is Alzheimer's disease and Parkinson's disease, which makes most of cases. New scientific challenges indicate that gut microbiota are directly associated with the progress of degenerative brain diseases through triggering metabolic diseases, modulating immune response, and changing diversity of microbial community. A high-valuable strategy is proposed for the management of these disorders and as an adjuvant for psychiatric treatment of degenerative brain diseases and other related metabolic diseases through modulation of the gut microbiota including probiotics.

• 오상남(전북대학교 동물자원과학과, Dept. of Animal Science and Institute of Milk Genomics, Chonbuk National University) | Sangnam Oh
• 김영훈(전북대학교 동물자원과학과, Dept. of Animal Science and Institute of Milk Genomics, Chonbuk National University) | Younghoon Kim
• 문용일(우석대학교 동물식품자원학과, Dept. of Animal Source Foods, Woosuk University) | Yong Il Moon Corresponding author