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발효 산삼배양근 효능평가 및 화장품 에멀젼 소재개발

Development of Emulsion and Evaluation of the Effectiveness of Wild Ginseng Adventitious Roots Using Fermentation Techniques

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  • URLhttps://db.koreascholar.com/Article/Detail/326293
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한국약용작물학회 (The Korean Society of Medicinal Crop Science)
초록

Background : Korean mountain ginseng (Panax ginseng C.A. Meyer) are difficult to industrially apply because of its scarcity and high cost. Advances in plant biotechnology have made it possible to produce mountain ginseng on a large scale using adventitious root cultures in bio-reactors. This study was conducted to develop a cosmetic emulsion using ginsenoside and physiological activity - enhanced raw materials by fermentation process. Methods and Results : Wild ginseng adventitious roots were fermented with Pediococcus pentosaceus HLJG 0702 (KACC 81017BP). ginsenoside contents was analysed by using HPLC. Antioxidant activity was measured by DPPH and ABTS radical scavenging activity and whitening effect was measured by tyrosinase inhibitory activity. After microfluidizer processing was performed to prepare emulsions with homogenized particles, particle size and distribution were measured through a transmission electron microscop e(TEM). Particle stability compares pH, viscosity, light and zeta potential. When fermented with Pediococcus pentosaceus HLJG 0702, the highest change rates of Rg3, Rk1 and Rg5 were shown and the antioxidant activity was increased. The whitening effect was 73.2 ± 0.9% when treated at 100 ㎍/㎖, 1.5 times higher than the control. The optimum particle size and distribution were shown to be 418.0 ± 14.9 ㎚ for 6 times treatment with 0 - 10 times microfluidizer treatment. Stability was about 3% in pH, viscosity and light test. the zeta potential was found to be homogeneous at –33.33 mV. Conclusion : Pediococcus pentosaceus HLJG 0702 Fermented Wild ginseng adventitious roots were found to have effective ingredients and improved physiological activity. We have also developed emulsions that exhibit optimal particle size and distribution

저자
  • Chul Joong Kim(Research Institute of Biotechnology, Hwajin Cosmetics) | 김철중
  • Yea Ji Lee(Research Institute of Biotechnology, Hwajin Cosmetics) | 이예지
  • Ki Hyun Kim(Research Institute of Biotechnology, Hwajin Cosmetics) | 김기현
  • Jae Hak Lee(Research Institute of Biotechnology, Hwajin Cosmetics) | 이재학
  • Kyung Cheol Kwon(Research Institute of Biotechnology, Hwajin Cosmetics) | 권경철
  • Seon Kang Choi(Department of Agricultural Life Sciences, Kangwon National University) | 최선강
  • Chang Yeon Yu(Department of Bio-Resource Sciences, Kangwon National University Bioherb Research Institute, Kangwon National University) | 유창연
  • Ji Hye Yoo(Bioherb Research Institute, Kangwon National University) | 유지혜
  • Jae Geun Lee(Research Institute of Biotechnology, Hwajin Cosmetics) | 이재근 Corresponding author