Physicochemical Properties and Biological Activity from Aerial Parts of Angelica gigas
Background : Aerial parts of Angelica gigas were studied in order to develop as functional pigment. The extracts were evaluated for physicochemical properties and biological activity. Methods and Results : Aerial parts of Angelica gigas were extracted by the rate of ethanol and distilled water. The extracts were evaluated for physicochemical properties by chromaticity, total sugar content, free sugar content, acidity, chlorophyll and carotenoids contents. Total sugar and acidity were 0.90 brix and 2.84% respectively. Chlorophyll and carotenoids contents were 0.24 and 0.04% respectively. The extracts were evaluated for biological activity by anti-inflammatory and anti-diabetes activity. Cell viabilities were measured by MTT assay. Effect of extracts on nitric oxide (NO) production from RAW264.7 cells was accessed by Griess reagent assay. Extracts to RAW 264.7 cells reduced amounts of nitrite by 76.0%. Conclusion : These results suggest that aerial parts of Angelica gigas Nakai may be useful pigment for anti-inflammatory and anti-diabetes activity.