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리모넨 들깨 부위별 분획별 추출물 생리활성 검정

Analysis of Biological Activity in Fraction Extracts from Limonene Perilla

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  • URLhttps://db.koreascholar.com/Article/Detail/326679
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한국약용작물학회 (The Korean Society of Medicinal Crop Science)
초록

Background : Perilla frutescens L. is valuable as a medicinal plant as well as a natural medicine and functional food. Limonene perilla collected from various places showed 60% limonene compounds. However biological activity of these accession has not been reported before. Therefore, this study was conducted to investigate the biological activity of limonene perilla. Methods and Results : Fractional solvent extracts were obtained by using organic solvents such as n-hexane, chloroform, ethyl acetate, n-BuOH, and aqueous solvent from different parts of limonene perilla extracted initially in 70% EtOH. We investigated the effects of limonene perilla on total phenol and flavonoid contents, FRAP (Ferric Reducing Antioxidant Power), total saponin contents and tyrosinase inhibition activity. Leaves of limonene perilla produced the highest total phenolic contents (29.88 mg·CAE/g), flavonoid (8.39 mg·QE/g) and saponin contents (47.77 mg·GIE/g) than stems and roots of limonene perilla. FRAP of leaves was 823.00±3.58 μM·FeSO4·E/mg. Tyrosinase inhibition activity rate was 40.31% in 70% ethanol extracts from leaves of limonene perilla. Conclusion : This results suggest that leaf of limonene perilla fractions has significant antioxidant activity. Also, limonene perilla could be used as a functional biomaterial in developing cosmetics and functional foods.

저자
  • Ji Hye Yoo(Bioherb Research Institute, Kangwon National University) | 유지혜
  • Jae Hoo Choi(Department of Bio-Resource Sciences, Kangwon National University) | 최재후
  • Chang Heum Kim(Department of Bio-Resource Sciences, Kangwon National University) | 김창흠
  • Byeong Ju Kang(Department of Bio-Resource Sciences, Kangwon National University) | 강병주
  • Mi Ran Jeon(Department of Bio-Resource Sciences, Kangwon National University) | 전미란
  • Su Jin Yang(Department of Herbal Medicine Resource, Kangwon National University) | 양수진
  • Si Young Lee(Department of Herbal Medicine Resource, Kangwon National University) | 이시영
  • Jung Dae Lim(Department of Herbal Medicine Resource, Kangwon National University) | 임정대
  • Seon Kang Choi(Department of Agriculture Life Sciences, Kangwon National University) | 최선강
  • Woo Jun Chung(Department of Bio-Resource Sciences, Kangwon National University) | 정우준
  • Myong Jo Kim(Bioherb Research Institute, Kangwon National University Department of Bio-Resource Sciences, Kangwon National University) | 김명조
  • Chang Yeon Yu(Bioherb Research Institute, Kangwon National University Department of Bio-Resource Sciences, Kangwon National University) | 유창연 Corresponding author