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한우 부분육 선호부위에 대한 ssGBLUP을 활용한 GWAS 분석 KCI 등재

A Genome-wide Association Study of Preferred Primal Cuts of Hanwoo Cattle Using Single-step GBLUP

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농업생명과학연구 (Journal of Agriculture & Life Science)
경상대학교 농업생명과학연구원 (Institute of Agriculture & Life Science, Gyeongsang National University)
초록

Data on primal cuts were collected from 1,829 steers of Hanwoo progeny testing programs, between 2010 and 2015 for the ssGWAS. SNP data were analyzed by using Illumina Bovine 50K Beadchip. The SNP data that matches with phenotype data was 674 animals. As a first step, the genomic estimated breeding value(GEBV) of the loin and rib cuts were estimated, which was used in the estimation of SNP marker effects and their variances related to the traits. Then, the estimated variance explained by each marker was expressed as a proportion to the total genetic variance. Finally, the SNP loci and their significance to any possible QTL were examined. Among the 20 best SNP loci explaining a larger proportion of SNP variance to the total genetic variance for tender loin yield, the region between 12,812,193 ~ 12,922,313bp on BTA 10 harbored a cluster of SNPs that explained about 7.32 to 7.34% of the total genetic variance. For strip loin yield, a peak for higher effects for multiple SNPs was found in BTA24, between 38,158,543 and 38,347,278bp distances, which explained about 8.36 to 8.56% of the observed variance for this trait. For loin yield had relatively smaller effects in terms of the total genetic variance. Therefore, loin yield might be affected by a few loci with moderate effects and many other loci with smaller effects across the genome.

저자
  • 이재구(농촌진흥청 국립축산과학원) | Jae Gu Lee (National Institute of Animal Science, RDA, Cheonan, 31000, Korea)
  • 박병호(농촌진흥청 국립축산과학원) | Byoungho Park (National Institute of Animal Science, RDA, Cheonan, 31000, Korea)
  • 박미나(농촌진흥청 국립축산과학원) | Mi Na Park (National Institute of Animal Science, RDA, Cheonan, 31000, Korea)
  • Alam M.(농촌진흥청 국립축산과학원) | M. Alam (National Institute of Animal Science, RDA, Cheonan, 31000, Korea)
  • 김시동(농촌진흥청 국립축산과학원) | Sidong Kim (National Institute of Animal Science, RDA, Cheonan, 31000, Korea)
  • 도창희(충남대학교 농업생명과학대학 낙농학과) | Changhee Do (Chungnam National University, Daejeon, 34134, Korea)
  • 최태정(농촌진흥청 국립축산과학원) | Tae Jeong Choi (National Institute of Animal Science, RDA, Cheonan, 31000, Korea) Corresponding author