Biochemical methane potential (BMP) of residual wastes from transesterification was tested to safely recycle carcass via rendering process. The carcass was obtained from a buried site for avian influenza (AI) infected poultry. Rendered lipid generated by a pilot-scale high-pressure rendering process was the main source of transesterification for biodiesel recovery. To test the feasibility of waste-to-energy approach for AI infected carcass, we compared the BMPs of various fractions of rendered materials from the carcass. BMP and specific methanogenic activity results indicate that transesterification waste shows better digestibility than that of rendered lipid, and the digestion performance was comparable to that of liquid residue. Biogas yields of glycerol, rendered lipids, and liquid residue were estimated as 0.11 L/g chemical oxygen demand (COD), 0.06 L/g COD, and 0.17 L/g COD, respectively. Regression analysis support that biogas production rate of glycerol (21 mL/g COD/d) was much faster than that of lipid (7 mL/g COD/d) while that of liquid residue was similar (24 mL/g COD/d). In summary using transesterification waste as a bioresource for bioenergy conversion can be a viable and sustainable option for the complete termination of burial site.