In this study, we assessed antioxidant, anti-diabetic, and anti-Alzheimer activities of Opuntia ficus-indica var. saboten (OFI) at harvest time. OFIs were cultivated December 2015~November 2016 in Jeju island. The 70% ethanol extracts of OFI were used to investigate total polyphenol and flavonoid contents, antioxidant(DPPH and ABTS radical scavenging assay), anti-diabetic(yeast α-glucosidase and rat α-glucosidase inhibition assay), and anti-Alzheimer(Acetylcholinesterase and butyrylcholinesterase inhibition assay) activities. Total polyphenol and flavonoid contents of OFIs were 17.40~23.11 μg garlic acid/mg Ex and 2.17~6.22 ug (+)-catechine/mg Ex, respectively. DPPH and ABTS radical scavenging activity of OFIs were 131.98~184.90 mg ascorbic acid(AA) eq/100 g and 63.60~101.83 mg AA eq/100 g, respectively. In the anti-diabetic and anti-Alzheimer activities, 70% ethanol extracts of OFI exhibited moderate inhibition activity, compared to control (acarbose and beberine). Total polyphenol and flavonoid contents, antioxidant, anti-diabetic, and anti-Alzheimer activities were no significant differences by season, respectively. Therefore, information on comparative biological evaluations of OFI may be a beneficial in exploring functional food and drug development.

서 론
 재료 및 방법
  1. 재료
  2. 추출물 조제
  3. 총 폴리페놀 및 총 플라보노이드 함량
  4. 항산화 활성 평가
  5. 항당뇨 활성 평가
  6. 항알츠하이머 활성 평가
 결과 및 고찰
  1. 총 폴리페놀 및 총 플라보노이드 함량
  2. 항산화 활성 평가
  3. 항당뇨 활성 평가
  4. 항알츠하이머 활성 평가
 요약 및 결론
 감사의 글
 References

• 정윤숙(농촌진흥청 국립농업과학원 농식품자원부) | Yun Sook Jeong (Dept. of Agrofood Resources, National Academy of Agricultural Science, Rural Development Administration)
• 황병순(농촌진흥청 국립농업과학원 농식품자원부) | Byung Soon Hwang (Dept. of Agrofood Resources, National Academy of Agricultural Science, Rural Development Administration)
• 조수묵(농촌진흥청 국립농업과학원 농식품자원부) | Soo-Muk Cho (Dept. of Agrofood Resources, National Academy of Agricultural Science, Rural Development Administration)
• 황경아(농촌진흥청 국립농업과학원 농식품자원부) | Kyung-A Hwang (Dept. of Agrofood Resources, National Academy of Agricultural Science, Rural Development Administration)
• 황인국(농촌진흥청 국립농업과학원 농식품자원부) | In Guk Hwang (Dept. of Agrofood Resources, National Academy of Agricultural Science, Rural Development Administration) Corresponding author