In order to study the effects of Aloe vera Linne treatment on the clinical chemistry in patients with liver disease, seven patients were administered orally with 800-1, 600 mg of Aloe vern Linne four times a day for six months. The high levels of serum AST, ALT, ALP, γ-GTP and total bilirubin in patients were significantly reduced by administration of Aloe vem L.. The reduced serum albumin/globulin value was increased by Aloe vera L. treatment. But other blood parameters of clinical chemistry values were not affected by Aloe very L. treatment. These data suggest that Aloe very L. can be effective in treatment of the patients with liver disease.