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화학물질의 건강 위해성 평가를 위한 수학 통계적 추계 모델링의 응용 KCI 등재

Application of Mathematical Modeling to Extraplate from High Dose to Low Dose for Risk Assessment of Vinyl Chloride

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한국식품위생안전성학회지 (Journal of Food Hygiene and Safety)
한국식품위생안전성학회 (Korean Society of Food Hygiene and Safety)
초록

This study was designed to predict the risk of a hazard chemical, vinyl chloride, by applying dose-response assessment that are one of the major process in practicing risk assessment. After extrapolating from the high dose exposure of vinyl chloride based upon animal carcinogenic data to the low dose exposed to human using several mathematical models, we calculated the cancer potency factors as well as virtually safe dose and the resulted values were compared. This process will provide the new insight to assess the risk of a chemical accurately imposed to human in the future.

저자
  • 이영조
  • 이승진
  • 이석호
  • 정진호