Antibiotic resistance of thirty strains of Shigella sonnei isolated from patient of Shigellosis outbreke at Young Cheon area in 1998 was tested. Twenty-seven strains were resistant to Tr(Trimethoprim-Sulfamethoxazol) and Shigella sonnei SG-8 was resistant to Tr(Trnnethoprim-Sulfamethoxazol), Ap(Ampicillin), Cp(Cephalothin) and Pi (Piperacillin). Shigella sonnei SG-49, SG-66, and SG-73 were senstive to all tested antibiotics. Physiological characteristics of isolated Shigella sonnei SG-8, SG-49, SG-57, and SG-73 such as effect of pH, NaCl concentration and temperature on the growth, survival in adverse condition and heat resistance were investigated Growth of the strains were inhibited at pH 4 and pH 9. All strains were grown in Tryptic soy broth containing 6% of NaCl but inhibited in TSB containing 9% of NaCl except Shigella sonnei SG-73 after incubation for 18hrs at 37℃. Selected strains grew during storage at 10 but did not grow at 4.1he strains were survived in 1 % pepton solution for 15 days at 37℃. Viable cell of selected strains were decrease 45 log cycle after heat treatment for 30 miss at 60℃ but did not detect by heat treatment for 5 wins at 70℃.

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