Peach seeds contain a large amount of phenolic components and exhibit excellent physiological effects in various diseases. We examined the antioxidant effects of stone and seed of three peach cultivars (Miwhang, MH; Kanoiwa hakuto, KH; and Cheonhong, CH) by 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay, ferric reducing activity of plasma (FRAP) assay, and cupric ion reducing antioxidant capacity (CUPRAC) reduction. The results showed that the stone extracts of CH had higher levels of total phenols and flavonoids than those of the other cultivars do, and the stone extracts of KH and CH have the potential to reduce DPPH, FRAP, and CUPRAC activities. In addition, we found that KH, MH, and CH stone extracts decreased nitric oxide generation in RAW 264.7 and BV2 cells. The total phenol and flavonoid contents had no significant correlation with anti-oxidant activities. On the other hand, the anti-inflammatory activity had a low linear correlation with anti-oxidant activities and total phenol and flavonoid contents. The present results suggest that the correlation between antioxidant and anti-inflammatory effects of stone and seed, and the appropriate combination of the stone and seed extracts could be used as an anti-inflammatory treatment and prevention material, respectively.

서 론
 재료 및 방법
  실험 재료
  시료 준비
  총 phenol 함량 분석
  총 flavonoid 함량 분석
  1.1-Diphenyl-2-picrylhydrazyl(DPPH) radical 소거 활성 측정
  Ferric ion reducing antioxidant power(FRAP) assay에 의한 환원력 측정
  Cupric ion reducing antioxidant capacity(CUPRAC) assay에 의한 환원력 측정
  세포 배양
  세포 독성
  Nitric oxide(NO) 라디칼 소거활성 측정
  통계처리
 결과 및 고찰
  총 phenol 함량 및 총 flavonoid 함량
  항산화 활성
  항염증 활성
  상관 관계
 요 약
 감사의 글
 References

• Kyung-Mi Jung(Cheongdo Peach Research Institute, GyeongSangBuk-Do Agricultural Technology Administration) | 정경미 Corresponding author
• Seung-hwa Baek(Department of Predictive Toxicology, Korea Institute of Toxicology) | 백승화