In the current research, a seismic ceiling system as one of non-structural elements in buildings has been developed by applying newly designed vertical hanger clips combined with M-bar channel clips. In order to evaluate the seismic performance of the developed system, full-scale shaking table tests of one story frame structure with the conventional ceiling system or the developed seismic ceiling system were performed with time-history responses under earthquake loads. The developed system was also evaluated by the time-history dynamic analysis. From seismic test and analysis, it was shown that the developed seismic ceiling system could give improved seismic performances to minimize displacements and damages of ceiling systems as well as enhance seismic safety of the ceiling system.