Clostridium perfringens (C. perfringens) 와 Mycobacterium fortuitum (M. fortuitum)은 동물과 사람에서 심각한 질병과 관련이 있는 세균들로 알려져 있다. 본 연구에서는, povidoneiodine을 주성분으로 하는 소독제의 살균효과를 C. perfringes와 M. fortuitum을 대상으로 평가하였다. 소독제의 살균효과는 배지희석법을 이용하여, 대상 세균들을 4℃에서 소독제에 30분 동안 노출시킨 다음, 가장 낮은 소독제의 살균 희석배수를 결정하였다. 소독제는 경수와 유기물로 희석하였으며, 경수 조건에서, C. perfringes와 M. fortuitum에 대해 효과적인 소독제 희석배수는 각각 50과 80배이었다. 유기물 조건에서는, C. perfringes와 M. fortuitum에 대해 효과적인 소독제 희석배수는 모두 15배로 나타났다. 이상의 결과로부터, povidone-iodine을 주성분으로 하는 소독제는 C. perfringes와 M. fortuitum에 대해 살균효과를 갖는 것으로 확인되었으며, C. perfringes와 M. fortuitum에 의한 질병의 확산을 방지하기 위해 사용될 수 있을 것으로 사료된다.

Clostridium perfringens (C. perfringens) and Mycobacterium fortuitum (M. fortuitum) are associated with considerable diseases in animals and human. In this study, the disinfection efficacy of a commercial disinfectant composed to povidone-iodine (PVI) was evaluated against C. perfringens and M. fortuitum. A bactericidal efficacy test by broth dilution method was used to determine the lowest effective dilution of the disinfectant following exposure to C. perfringens and M. fortuitum for 30 min at 4℃. The disinfectant and test bacteria were diluted with hard water (HW) or organic matter suspension (OM) according to treatment condition. On HW condition, the bactericidal activity of the disinfectant against C. perfringens and M. fortuitum was 50 and 80 fold dilutions, respectively. On OM condition, the bactericidal activity of the disinfectant against both C. perfringens and M. fortuitum was 15 fold dilutions. As the disinfectant composed to PVI possesses bactericidal efficacy against C. perfringens and M. fortuitum, the disinfectant solution can be used to control the spread of bacterial diseases.

ABSTRACT
 Materials and methods
  Bacteria and culture
  Disinfectant
  Diluents and treatment condition
  Experimental procedures
  Results
 Discussion
 요 약
 Acknowledgements
 References

• Chun-Nam Cha(Engineering Research Institute, Department of Industrial Systems Engineering, Gyeongsang National University)
• Eun-Kee Park(Department of Medical Humanities and Social Medicine, College of Medicine, Kosin University)
• Youyoung Cho(Department of Nursing, Hanyeong College)
• Chang-Yeul Yoo(Department of Computer Information, Gyeongnam Provincial Namhae College)
• Engin Tutkun(Ankara Occupational Diseases Hospital, Ministry of Health)
• Suk Kim(Research Institute of Live Sciences, College of Veterinary Medicine, Gyeongsang National University)
• Hu-Jang Lee(Research Institute of Live Sciences, College of Veterinary Medicine, Gyeongsang National University) Correspondence to