Pohang earthquake occurred on November 15, 2017, with a magnitude of 5.4. The damage of the structure caused by the Pohang earthquake was the most significant in 4-story piloti-type buildings, where the damage patterns were different according to the location of columns and walls at the first story. One building with a staircase at a corner shows shear failure at columns, and Another building with a staircase in the middle shows no failure or shear failure at staircase walls. Therefore, two different piloti-type buildings were selected; one has a staircase at a corner and another has in the middle, and the seismic behavior of the buildings were examined by nonlinear dynamic analysis applying a ground motion measured at Pohang. Analytical model well simulated the actual behavior of the piloti-type buildings during the earthquake. Analysis results showed that walls have an insufficient shear strength wherever the location of the staircase is and columns with insufficient transverse reinforcement could be failed when the staircase is located at a corner. Conclusively, structural engineers should design columns and walls in piloti-type buildings to possess sufficient capacity according to the location of staircase.