This work aimed to discriminate the geographical origins of Domestic and Chinese Wolfiporia extensa. subjected to of oxygen (45.32 to 48.07%), carbon (38.09 to 40.12%), hydrogen (6.05 to 6.78%), and nitrogen (0.16 to 0.23%). Antioxidant activity was examined by DPPH free radical scavenging activity. According to the results of the experiment, no significant differences were found between domestic (IC50, 7.25 mg/ml) and Chinese (IC50, 8.35 mg/ml) Poria cocos wolf. However, as determined by the inorganic mineral contents were significantly different between domestic and Chinese W. extensa. The amount of potassium in domestic and Chinese W. extensa was 47.60 ± 8.78% and 33.14 ± 17.27%, respectively. The results of this study suggested that the analysis of inorganic components by ED-XRF should be useful for origin identification of Poria cocos wolf.