In this study, TMD(Tuned Mass Damper) is installed in a retractable-roof spatial structure in order to investigate dynamic response characteristics according to mass ratio and installed position of TMD on large spatial structures. The example analytical model is generated based on the Singapore sports hub stadium. Twenty eight analytical models are used to investigate optimal installation position of TMD for the example retractable-roof spatial structure using 4 to 16 TMDs. The mass of one TMD is set up 1% of total mass at the example analytical model. Displacement response ratio of model with TMD is compared with that of base model without TMD. It has been found from numerical simulation that it is more effective to install TMD at the edge of the spatial structure rather than to concentrate the TMD at the center of the spatial structure.