This paper presents the design, analysis, and experimental evaluations of precast reinforced UHPC (ultra high-performance concrete) beams with a new design concept of non-uniform flexural members. With outstanding mechanical properties of UHPC which can develop the compressive strength up to 200MPa, the tensile strengths up to 8~20MPa and the tensile strain up to 1~5%, a non-uniform structural shape of UHPC flexural beams were optimally designed using three-dimensional finite element analysis. The experiments were carried out and compared with the design strength in order to verify the performance of them. Proposed non-uniform UHPC beams were evaluated by a series of three-point beam loading test as well as estimated by design bending and shear strength of members. The newly designed UHPC beams show excellent performances not only in transverse load capacities but also in deformation capacities.