In photobiophysics, biophoton means a kind of biological energy which enhances most metabolisms of the body. To investigate the immuno-enhancing effects of biophoton energy projector (BEP) producing light energy, pigs were irradiated with BEP for 8 weeks. Swine peripheral blood mononuclear cells (sPBMCs) were isolated from the blood of irradiated pigs. In this study, the antigen uptake and mitochondrial membrane potential of sPBMCs were measured by flow cytometric analysis. The irradiation of BEP increased the antigen uptake of sPBMCs. For functional analysis, the production of Bordetella bronchiseptica-specific IgG, measured using antigen-specific ELISA, was increased during the period of BEP irradiation. Taken together, the results suggest that the irradiation of BEP has immune-enhancing effects on sPBMCs.

Abstract
 서 론
 재료 및 방법
  실험동물 및 시험균
  실험동물의 배치
  Peripheral blood mononuclear cells (PBMCs)의 분리
  유세포분석
  혈청에서 B. bronchiseptica 항원 특이적인 항체가의 측정
  유의성 분석
 결 과
  돼지 PBMCs의 antigen uptake 변화
  돼지 PBMCs의 미토콘드리아 막전위의 변화
  B. bronchiseptica 항원 특이적인 항체 생산량의 증가
 고 찰
 REFERENCES

• Yohan Ko(Laboratory of Veterinary Pharmacology, College of Veterinary Medicine, Jeju National University)
• Deokho Ko(Laboratory of Veterinary Pharmacology, College of Veterinary Medicine, Jeju National University)
• Hong-Gu Joo(Laboratory of Veterinary Pharmacology, College of Veterinary Medicine, Jeju National University) Corresponding Author