Porcine epidemic diarrhea virus (PEDV) causes porcine epidemic diarrhea (PED) and a considerable economic loss in the swine industry. In this study, the virucidal efficacy of a disinfectant composed of citric acid, benzalkonium chloride and phosphoric acid against PEDV was investigated. Virucidal efficacy was assessed as the infectivity of PEDV toward Vero cells after exposure of the virus to the disinfectant. PEDV was exposed to the disinfectant in the presence of either hard water (HW) or an organic matter suspension (OM). In HW condition, PEDV was inactivated by 600-fold dilutions of the disinfectant. In the presence of OM, the disinfectant showed virucidal activity after a 200-fold dilution. As the disinfectant possesses virucidal activity against PEDV, it should be an effective reagent to use to limit the spread of animal viral diseases.

INTRODUCTION
 MATERIALS AND METHODS
  Disinfectant
  PEDV and cell culture
  Diluents and treatment conditions
  Virus-disinfectant contact reaction
  Evaluation of the disinfectant against PEDV
 RESULTS AND DISCUSSION
 ACKNOWLEDGEMENTS
 REFERENCES

• Chun-Nam Cha(Engineering Research Institute, Department of Industrial Systems Engineering, Gyeongsang National University)
• Chang-Yeul Yoo(Department of Computer Information, Gyeongnam Provincial Namhae College)
• Suk Kim(Research Institute of Live Sciences, College of Veterinary Medicine, Gyeongsang National University)
• Hu-Jang Lee(Research Institute of Live Sciences, College of Veterinary Medicine, Gyeongsang National University) Corresponding Author