This study examined the potentials for greenhouse gas reduction by material recovery and energy recovery from municipal solid waste between 2017 and 2026 in Daejeon Metropolitan City (DMC), which is trying to establish a material-cycle society by constructing a waste-to-energy town by 2018. The town consists of energy recovery facilities such as a mechanical treatment facility for fluff-type solid refuse fuel (SRF) with a power generation plant and anaerobic digestion of food waste for biogas recovery. Such recycling and waste-to-energy facilities will not only reduce GHGs, but will also substitute raw materials for energy consumption. The emissions and reduction rate of GHGs from MSW management options were calculated by the IPCC guideline and EU Prognos method. This study found that in DMC, the decrease of the amount of MSW landfilled and the increase of recycling and waste-to-energy flow reduced GHGs emissions from 167,332 tonCO2 eq/yr in 2017 to 123,123 tonCO2 eq/yr in 2026. Material recycling had the highest rate of GHG reduction (-228,561 tonCO2 eq/yr in 2026), followed by the solid refuse fuels (-29,146 tonCO2 eq/yr in 2026) and biogas treatment of food waste (-3,421 tonCO2 eq/yr in 2026). This study also shows that net GHG emission was found to be -30,505 tonCO2 eq in 2017 and -105,428 tonCO2 eq, indicating a great and positive impact on future CO2 emission. Improved MSW management with increased recycling and energy recovery of material waste streams can positively contribute to GHGs reduction and energy savings. The results of this study would help waste management decision-makers clarify the effectiveness of recycling MSW, and their corresponding energy recovery potentials, as well as to understand GHG reduction by the conversion.