Purpose: The current study explored differences in psychosocial variables by the physical activity stages in a random sample of middle aged adults, and identified the relationship of physical activity with psychosocial variables. Methods: A total of 426 adults aged from 40 to 59 years old who reside in Nowon-gu, Seoul were voluntarily participated in the study. The study participants responded stage of change scale for physical activity, global physical activity questionnaire, self-efficacy scale, decisional balance scale, and social support. Frequency analysis, descriptive analysis, MANOVA, Correlation analysis, and regression analysis were applied using SPSS 20.0. Results: Results indicated that except perceived barriers self-efficacy, perceived benefits, friend support, and family support increased significantly across the stages of physical activity. Furthermore, based on the regression analysis, the most important predictors of physical activity in a descending order of significance were family support, self-efficacy, perceived benefits, and friend support, and family support The total variance in physical activity explained by these variables was 48%. Conclusion: The present study offers a starting point for practical interventions aimed at increasing physical activity levels of middle aged adults in healthcare settings, and also encourages and supports healthcare providers who are working in the community to increase their knowledge of physical activity and its related psychosocial variables.