This study was carried out to predict the current and future potential distribution and to identify the factors affecting potential distribution of 7 plants (Lamium amplexicaule L., Trigonotis peduncularis (Trevir.) Benth. ex Hemsl, Capsella bursa-pastoris (L.) L. W. Medicus, Taraxacum officinale Weber, Veronica persica Poir., Conyza sumatrensis E. Walker, Hypochaeris radicata L.) selected as indicators for climate change in agricultural ecosystem. We collected presence/absence data of 7 indicator plants at 108 sites in South Korea and applied the Maxent model. According to future climate scenario, the distribution area of C. bursa-pastoris (L.) L. W. Medicus, T. officinale Weber, and V. persica Poir. was expected to be reduced, but the distribution range was to be maintained. The distribution areas and range of the C. sumatrensis E. Walker and H. radicata L. were expected to be increased. The distribution area and range of T. peduncularis (Trevir.) Benth. Ex Hemsl. and L. amplexicalue L. were rapidly decreased. Non-climatic factors such as land cover and altitude were the most important environmental variable for T. officinale Weber, C. bursa-pastoris (L.) L.W.Medicus, V. persica Poir., T. peduncularis (Trevir.) Benth. Ex Hemsl., and L. amplexicalue L.. Climatic factors were the most important environmental variable for C. sumatrensis E. Walker and H. radicata L.. It is expected that the future potential distribution of 7 indicator plants response to climate change will be used to monitor and to establish the management plan.