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Influence of Acute Respiratory Virus Infection on Kawasaki Disease

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The Medical Journal of Chosun University (조선대학교 의대논문집)
조선대학교 의학연구원 (Institute of Medical Science, Chosun University)
초록

The aim of this study was to determine the effect of acute respiratory viral infection on Kawasaki disease. From July 2016 to June 2018, among the patients who underwent respiratory virus screening at the Kwangju Christian Hospital, those diag-nosed 88 patients with Kawasaki disease were enrolled in this study. The effects of acute respiratory viral infection on Ka-wasaki disease were compared according to whether 2nd intravenous immunoglobulin (IVIG) treatment was administered or not, and whether coronary artery complications occurred. Respiratory virus was detected in 44 out of 88 patients. 2nd IVIG treatment rates were 16% (n=7) and 27% (n=12) in the virus positive group and the virus negative group, respectively (p>0.05). The incidence of coronary artery complications was 11% (n=5) and 25% (n=11) in the virus positive group and the virus negative group, respectively (p>0.05). There was no statistically significant correlation between the 2nd IVIG admin-istration and coronary artery complications following the detection of respiratory virus in patients with Kawasaki disease. We think it is necessary to actively study the effects of acute respiratory viral infection on Kawasaki disease through large-scale studies of multiple centers in the future.

목차
서 론
 대상 및 방법
  대상
  방법
 결 과
  일반적 특성
  호흡기 바이러스 검출 및 분포
  바이러스 유무에 따른 임상 양상의 비교
 고 찰
 참고문헌
저자
  • 이화랑(광주기독병원 소아청소년과) | Hwoa Rang Lee (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 조철준(광주기독병원 소아청소년과) | Chul Jun Cho (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 김용욱(광주기독병원 소아청소년과) | Yong Wook Kim (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 김경심(광주기독병원 소아청소년과) | Kyoung Sim Kim (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 김은영(광주기독병원 소아청소년과) | Eun Young Kim (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 김령(광주기독병원 소아청소년과) | Young Kim (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 장해인(광주기독병원 소아청소년과) | Hae In Jang (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea)
  • 조형민(광주기독병원 소아청소년과) | Hyoung Min Cho (Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea) Corresponding author