Neutropenia is a common finding in pediatrics with 1.5-9% of children (without malignancy) presenting to hospital found incidentally to be neutropenic. The majority of these pediatric patients with transient neutropenia present with infectious symptoms with an infectious agent proven in approximately 50% of cases, most commonly viral in nature. 270 children, who were diagnosed with influenza infection at the Chosun University Hospital during a 8-year period, were included in the study. Clinical and laboratory feature were analyzed. 46 patients (17%) were neutropenic with no identifiable cause other than the influenza. The incidence of leukopenia was significantly higher in association with influenza B than influenza A (24.0% vs 12.3%). Period from the onset of fever to lymphopenia was significantly longer in association with neutropenia (+) group than neutropenia (−) group. Recovery period of neutropenia was mean 4 days (range 3-7 days). We conclude that mild, transient neutropenia is common among patients with influenza infection and advise that it should not cause alarm or invite specific investigation unless severe or prolonged.

서 론
 대상 및 방법
 결 과
  대상 환자군의 특성
  Influenza A와 B군의 비교
  중성구감소증 발생군의 특성
 고 찰
 참고문헌

• 박형철(조선대학교 의학전문대학원 소아청소년과 교실) | Hyong Chul Park (Department of Pediatrics, Chosun University School of Medicine, Gwangju, Korea)
• 이재희(조선대학교 의학전문대학원 소아청소년과 교실) | Jae Hee Lee (Department of Pediatrics, Chosun University School of Medicine, Gwangju, Korea) Corresponding author